MAT Subtypes and Neurotransmission (P40578)
MAT Subtypes and Neurotransmission
The Monoamine Transporter (MAT) is a protein that plays a crucial role in the transport of various neurotransmitters in the brain. It is a transmembrane protein that is expressed in various tissues and cells, including the brain, and is involved in the regulation of neurotransmitter release and uptake. MAT has four subtypes, including MAT1, MAT2, MAT3, and MAT4, which differ in their localization, stability, and function.
MAT1 is the most abundant MAT subtype and is expressed in the brain, heart, and testes. It is involved in the transport of dopamine (D2), serotonin (5-HT), and norepinephrine (NE). MAT1 function is critical for the proper functioning of the brain and has been implicated in various neurological disorders, including Parkinson's disease, addiction, and depression.
MAT2 is the MAT subtype that is predominantly expressed in the brain and is involved in the transport of dopamine (D2), norepinephrine (NE), and serotonin (5-HT). MAT2 function is critical for the proper functioning of the brain and has been implicated in various neurological disorders, including Parkinson's disease, addiction, and depression.
MAT3 is the MAT subtype that is expressed in various tissues and cells, including the brain, heart, and testes, and is involved in the transport of dopamine (D2), serotonin (5-HT), and norepinephrine (NE). MAT3 function is important for the proper functioning of the brain and has been implicated in various neurological disorders, including epilepsy and schizophrenia.
MAT4 is the MAT subtype that is expressed in various tissues and cells, including the brain, heart, and testes, and is involved in the transport of dopamine (D2), serotonin (5-HT), and norepinephrine (NE). MAT4 function is important for the proper functioning of the brain and has been implicated in various neurological disorders, including Parkinson's disease, addiction, and depression.
MAT has been identified as a potential drug target due to its involvement in various neurological disorders. For example, MAT1 has been shown to be involved in the regulation of neurotransmitter release and uptake in the brain, and MAT2 has been shown to play a role in the regulation of sensory processing in the brain. MAT3 and MAT4 have also been shown to be involved in the regulation of neurotransmitter release and uptake in the brain.
In addition to its involvement in neurotransmission, MAT is also involved in the regulation of inflammation in the brain. MAT has been shown to play a role in the regulation of inflammation in the brain, and MAT4 has been shown to be involved in the regulation of immune cell function in the brain.
MAT has also been shown to be involved in the regulation of cell survival and proliferation in the brain. MAT1 has been shown to play a role in the regulation of cell survival and proliferation in the brain, and MAT3 has been shown to play a role in the regulation of cell survival and proliferation in the brain.
MAT has been implicated in various neurological disorders, including Parkinson's disease, addiction, and depression. For example, MAT1 has been shown to be involved in the regulation of neurotransmitter release and uptake in the brain, and MAT2 has been shown to play a role in the regulation of sensory processing in the brain. MAT3 and MAT4 have also been shown to be involved in the regulation of neurotransmission and uptake in the brain.
In addition to its involvement in neurotransmission and regulation of inflammation, MAT is also involved in the regulation of cell survival and proliferation in the brain. MAT1 has been shown to play a role in the regulation of cell survival and proliferation in the brain, and MAT3 has been shown to play
Protein Name: Monoamine Transporter (MAT) (nonspecified Subtype)
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MORC1 | MORC2 | MORC2-AS1 | MORC3 | MORC4 | MORF4 | MORF4L1 | MORF4L1P1 | MORF4L1P3 | MORF4L1P7 | MORF4L2 | MORF4L2-AS1 | MORN1 | MORN2 | MORN3 | MORN4 | MORN5 | MOS | MOSMO | MOSPD1 | MOSPD2 | MOSPD3 | MOV10 | MOV10L1 | MOXD1 | MOXD2P | MPC1 | MPC2 | MPDU1 | MPDU1-AS1 | MPDZ | MPEG1 | MPG | MPHOSPH10 | MPHOSPH10P1 | MPHOSPH6 | MPHOSPH8 | MPHOSPH9 | MPI | MPIG6B | MPL | MPLKIP | MPND | MPO | MPP1 | MPP2 | MPP3 | MPP4 | MPP7 | MPPE1 | MPPED1 | MPPED2 | MPPED2-AS1 | MPRIP | MPST | MPTX1 | MPV17 | MPV17L | MPV17L2 | MPZ | MPZL1 | MPZL2 | MPZL3 | MR1 | MRAP | MRAP2 | MRAS | MRC1 | MRC2 | MRE11 | MREG | MRFAP1 | MRFAP1L1 | MRGBP | MRGPRD | MRGPRE | MRGPRF | MRGPRF-AS1 | MRGPRG | MRGPRX1 | MRGPRX2 | MRGPRX3 | MRGPRX4 | MRI1 | MRLN | MRM1 | MRM2 | MRM3 | MRNIP | MRO | MROCKI | MROH1 | MROH2A | MROH2B | MROH3P | MROH5 | MROH6 | MROH7 | MROH7-TTC4 | MROH8